The global gene expression market size is anticipated to reach USD 19.4 billion by 2028 registering a CAGR of 9.96% from 2021 to 2028, according to a new report by Grand View Research, Inc. Rise in investments for the development of alternative drug discovery approaches coupled with an increase in research activities for genetic studies is expected to drive the global market.
Gene Expression Market Report Highlights
- cDNA synthesis & conversion dominated the process segment in 2020. High demand for personalized medicine coupled with technological advancements in sequencing techniques has enhanced the application of cDNA synthesis to produce genomic libraries
- Moreover, the introduction of systems that provide direct library synthesis has eliminated the need for prior steps, which increases revenue share
- Kits and reagents product generated the largest revenue in 2020 due to their high usage during the process
- In addition, ongoing innovation in the kits and reagents dedicated for specific applications contributes to the highest share of the segment
- High-Plex capacity is expected to register the fastest CAGR during the forecast period owing to the higher accuracy and increased application in cancer research
- RNA exp. was the largest revenue-contributing technique in 2020 owing to higher adoption of RNA exp. analysis
- Moreover, the introduction of high-throughput validation methods, such as targeted RNA sequencing, which are useful in broader screening technologies, has increased the revenue generation in the segment
- The drug discovery & development segment accounted for the largest revenue share in 2020 as Gene Exp. Signature (GES) is commonly used for the development of novel molecules for multifactorial cellular diseases like cancer, diabetes, tuberculosis, malaria, AIDS, and other infectious diseases
- North America was the dominant regional market in 2020. This can be attributed to the high adoption of advanced gene exp. technology in the region
- Major market participants, such as Thermo Fisher Scientific, Inc. and Agilent Technologies, have undertaken strategic initiatives to strengthen their position in the market
- In March 2020, Thermo Fisher Scientific, Inc. launched the PowerTrack SYBR Green PCR Master Mix for real-time PCR workflow. The product is intended to amplify targets for precise analysis
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Integrating gene expression data with other omics datasets, such as genomics, epigenomics, and proteomics, has gained attention. By combining multiple layers of molecular information, researchers can gain a more comprehensive understanding of gene regulation, interactions, and signaling pathways. The increasing complexity and volume of gene expression data have led to the development of sophisticated bioinformatics and computational tools. These tools aid in data preprocessing, normalization, differential expression analysis, pathway analysis, and functional enrichment, enabling researchers to extract meaningful insights from large-scale gene expression datasets. Gene expression profiling has been instrumental in drug discovery and development. By examining the gene expression patterns in diseased tissues or cells, researchers can identify potential drug targets and biomarkers for patient stratification and personalized treatment approaches. The demand for gene expression assays, including quantitative polymerase chain reaction (qPCR) and microarray-based technologies, remains strong. These assays continue to be widely used due to their simplicity, cost-effectiveness, and ability to provide targeted gene expression information.
A rise in awareness about the potential application of genetic studies has led to an increase in investments for the development and launch of novel products. For instance, in August 2020, Lexogen GmbH launched the QuantSeq-Pool Sample-Barcoded 3’ mRNA-Seq Library Prep Kit to expedite multiplexing capacities during gene expression profiling. The company’s new QuantSeq-Pool kit also facilitates the sequencing of up to 36,864 RNA samples in parallel, thereby reducing cost and time.
Furthermore, the decrease in cost associated with sequencing posed as a major driver in the last few years. According to the National Human Genome Research Institute (NHGRI), the cost of sequencing per genome reduced from USD 46.77 thousand in 2010 to USD 0.689 thousand in 2020. This dramatic 98.5% decline in sequencing costs within a decade has increased research involving genomic expression profiling studies.
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Gene Expression Market Insights By Region
North America held the largest revenue share. This can be attributed to the presence of a significant number of key players, such as Thermo Fisher Scientific, in the region. Asia Pacific is estimated to be the fastest-growing regional market, owing to the rising interest of dominant players in emerging markets, such as China and India. Sequencing and array technologies are widely adopted in this region owing to increased genomic and gene-related studies. Japan maintains its data repositories, such as DNA Data Bank of Japan (DDBJ) and Kyoto Encyclopedia of Genes and Genomes. These provide tools, such as GenomeNet Bioinformatics Tools, for sequencing, genome, and chemical analysis.
Competitive Analysis By Major Players
Most of the market leaders follow organic growth strategies to reinforce their market presence. Some of the prominent players in the global gene expression market include: QIAGEN; Quest Diagnostics, Inc.; F. Hoffmann-La Roche Ltd.; Illumina, Inc.; PerkinElmer, Inc.; Bio-Rad Laboratories; Thermo Fisher Scientific, Inc.
Grand View Research has segmented the global gene expression market on the basis of process, product, capacity, technique, application, and region.
Research Methodology
We employ a comprehensive and iterative research methodology focused on minimizing deviance in order to provide the most accurate estimates and forecasts possible. We utilize a combination of bottom-up and top-down approaches for segmenting and estimating quantitative aspects of the market. Data is continuously filtered to ensure that only validated and authenticated sources are considered. In addition, data is also mined from a host of reports in our repository, as well as a number of reputed paid databases. Our market estimates and forecasts are derived through simulation models. A unique model is created and customized for each study. Gathered information for market dynamics, technology landscape, application development, and pricing trends are fed into the model and analyzed simultaneously.
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About Grand View Research
Grand View Research provides syndicated as well as customized research reports and consulting services on 46 industries across 25 major countries worldwide. This U.S. based market research and consulting company is registered in California and headquartered in San Francisco. Comprising over 425 analysts and consultants, the company adds 1200+ market research reports to its extensive database each year. Supported by an interactive market intelligence platform, the team at Grand View Research guides Fortune 500 companies and prominent academic institutes in comprehending the global and regional business environment and carefully identifying future opportunities.
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